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PCBs Profile – Serum

The Polychlorinated Biphenyls (PCBs) Profile can help identify which of the most toxic PCBs a patient has been exposed to and the body burden of the patient. We look at the most commonly found PCBs, which have national reference ranges, that have been documented to cause adverse health problems. Levels are given both in parts per million (PPM) and as lipid-adjusted amounts so the clinician can best estimate the total body burden of these compounds.

Once PCBs enter the body, they are absorbed by our fat cells and stored. Since PCBs are not water-soluble, they are not excreted from the body and accumulate over a person’s lifetime. Increasing that person’s body burden of PCBs. Polychlorinated biphenyl testing can help you determine the extent of this PCB burden.

In adults, a heavy burden of PCBs over time can cause impairments to the brain, nervous system, endocrine system, and immune system, and may cause fertility issues.

A PCB burden affects children more than adults. PCBs are most often passed tom children through breastfeeding and trans-placental transfer. PCB exposure in children can impede neurobehavioral and immune system development. These impediments may cause delayed neurobehavioral development in motor skills and short term memory, and lower scores on intelligence, psychomotor, and behavioral tests. A lowered immune system can create many problems in children including allergies, sensitivities, and chronic infections.

PCBs were used as lubricants and coolants in transformers, capacitors, and electronic equipment because of high resistance to heat. Due to the stability of PCBs, unfortunately they do not breakdown in the environment and bioaccumulate in animals and humans.

PCBs were banned in the US in 1979 by the Environmental Protection Agency (EPA). However, due to the persistence of PCBs in the environment, PCBs continue to leach into the soil and groundwater from hazardous waste sites and lad fills. Since PCBs bioaccumulate, we are exposed through our food chain by eating fish, meat, and dairy products, especially from areas of the country considered contaminated.

Symptoms of PCB exposure are the following:

Severe acne


Eye Irritation

Liver damage

Weakened immune system

Chemical sensitivity




Certain cancers

This service is provided through Hoffman Clinic for Optimal Health.PCB toxicity is more prevalent than you think. Call today, 813-985-1322, if you suspect you have this problem.

Kelly Miller DC NMD FASA FBAARM CFDMP*, physician at Hoffman Clinic for Optimal Health.

*There is currently no licensure for Naturopathic Physicians (NMD) in the state of Florida and the Florida Board of Chiropractic Medicine does not currently recognize the credentialing of the  Fellowship from the Brazil-American Academy for Aging and Regenerative Medicine (FBAARM), or the Certification in Functional Diagnostic Medicine (CFDMP) from Functional Medicine University.